Transmission electron micrographs showing annulate lamellae from a frog oocyte. Annulate lamellae consist of stacked sheets of membrane containing closely packed structures resembling nuclear pores a...

Transmission electron micrograph of a thin section of the nucleus of a HeLa cell with mutant ALADIN. This grazing section of the nucleus shows en face views of nuclear pores which appear to have a no...

Transmission electron micrograph of a thin section of the nucleus of a HeLa cell expressing mutant ALADIN. Pore structure appears to be unaffected in the mutant. From a study of the role of the nuclea...

This Drosophila melanogaster early embryo (cycles 10-12) was injected with a fluorescent protein containing a nuclear localization signal (GFP-NLS). Proteins that contain a NLS are recognized by impor...

Fluorescence images showing the distribution of GFP-ALADIN, a WD-repeat protein that is mutated in the human triple A syndrome (green), and the nucleoporin Nup358(red)within the nuclear envelope of He...

Fluorescence images showing the distribution of GFP-ALADIN, a WD-repeat protein that is mutated in the human triple A syndrome (green), and Tpr, a nucleoporin that localizes to the nucleoplasmic filam...

Transmission electron micrograph of a thin section of the nucleus of a normal HeLa cell showing detail of a cross section of a nuclear pore - from a study of the role of the nuclear porin ALADIN. Oth...

Transmission electron micrograph of a thin section of the nucleus of a normal HeLa cell showing a tangential view of the nuclear envelope with nuclear pores. From a study of the role of the nuclear po...

The image shows a slice through a 3D tomographic reconstruction of a mouse adenocarcinoma cell based on x-ray microscopy. Live cells were cryofixed by plunge freezing in liquid ethane and the vitrifi...

The image shows a slice through a 3D tomographic reconstruction of a mouse adenocarcinoma cell based on x-ray microscopy. Live cells were cryofixed by plunge freezing in liquid ethane and the vitrifi...